If you or someone you care for has reached a stage of prostate cancer at which prostatectomy or radiation therapy was not successful in curing the cancer, or is not likely to be effective, you need to know that there are still options.

Lupron Depot is used to help relieve the symptoms of advanced prostate cancer, such as bone pain and difficulty urinating. Lupron Depot can slow the growth of cancerous cells. Individual results may vary. Lupron Depot is not a cure for prostate cancer.

Lupron Depot is the most prescribed* drug in a class of drugs known as luteinizing hormone-releasing hormone agonists, also called LH-RH agonists. In fact, Lupron Depot has been used since 1989 for the treatment of symptoms related to advanced prostate cancer.

Lupron Depot shuts down the production of testosterone by the testicles. This deprives hormone-dependent prostate cancer cells of the fuel (ie, testosterone) they need to grow. Individual results may vary. Decreasing the amount of testosterone in the body can result in a reduction of symptoms related to advanced prostate cancer.

Patients with advanced prostate cancer who are considering treatment with hormonal therapy should be aware of the potential benefits of starting immediate treatment with hormonal therapy, rather than waiting. Study results from 934 patients with advanced prostate cancer showed that the risk of serious complications decreases with early hormonal therapy. Patients who received immediate hormonal treatment experienced fewer bone fractures, spinal cord compressions, and urinary blockages, and the cancer was less likely to spread to non-bony tissues.

One of the most important things you can do is to think of your doctor as a partner in your care. Before doctor visits, spend some time thinking about the questions you'll want answered. Being prepared in advance can help you talk to your doctor. For questions about Lupron Depot, download and print our free Lupron Depot Questions to Ask Your Doctor

Dosage/Length of Therapy

Lupron Depot is an intramuscular injection that gives you and your physician the convenient choice of three dosing options:

• Lupron Depot–4 Month 30mg
  Given once every 4 months (16 weeks)
• Lupron Depot–3 Month 22.5mg
  Given once every 3 months (12 weeks)
• Lupron Depot 7.5mg
  Given once monthly

Learn about what to expect during therapy with Lupron Depot.

* Based on IMS Health, DDD™ and NDC Health, NDC non-retail™, September 2005 for the U.S. market.

IMS Health, DDD™ and NDC Health, NDC Non-Retail™ are not trademarks of TAP Pharmaceutical Products Inc.